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Related Concept Videos

Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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Accessory Structures of the Skin: Sweat Glands01:20

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Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
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Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Knee Joint01:23

Knee Joint

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The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
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Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Related Experiment Video

Updated: Apr 23, 2026

Knee Arthrocentesis in Adults
04:41

Knee Arthrocentesis in Adults

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Eccrine spiradenoma in knee.

A Sharma1, P Sengupta2, Anjan Kumar Das3

  • 1Department of Pathology, College of Medicine and Sagore Dutta Hospital, Kamarhati, Kolkata, India.

Indian Journal of Dermatology
|October 7, 2014
PubMed
Summary
This summary is machine-generated.

This case report details an uncommon benign eccrine spiradenoma in a 35-year-old man. The tumor showed cytological atypia but has not recurred, highlighting a rare presentation of this sweat gland tumor.

Keywords:
Cytological atypiabenign adenexal tumoureccrine spiradenomaeccrine sweat gland

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Eccrine spiradenoma is a rare, benign tumor originating from eccrine sweat glands.
  • Typically affects young adults without gender bias, malignant transformation is infrequent.

Purpose of the Study:

  • To report a unique case of eccrine spiradenoma in a 35-year-old male.
  • To document the clinical presentation, cytological findings, and follow-up of this rare adnexal tumor.

Main Methods:

  • Case presentation of a 35-year-old male with a right knee swelling.
  • Cytological evaluation of the lesion.
  • Clinical follow-up to assess recurrence.

Main Results:

  • Diagnosis of eccrine spiradenoma with cytological atypia.
  • The patient has shown no recurrence to date.
  • The lesion presented as a swelling over the right knee.

Conclusions:

  • Eccrine spiradenoma can present with cytological atypia.
  • This case highlights the importance of accurate diagnosis and monitoring of benign adnexal tumors.
  • Long-term follow-up is crucial for rare tumors like eccrine spiradenoma.