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In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Author's Reply

Chembolli Lakshmi1

  • 1Department of Dermatology, PSG Hospitals and PSG Institute of Medical Sciences and Research (PSGIMSR), Coimbatore, Tamil Nadu, India.

Indian Journal of Dermatology
|October 7, 2014
PubMed
Summary

No abstract available in PubMed .

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