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Updated: Apr 23, 2026
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Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
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[Refractory hypertension: diagnosis and treatment optimization].
Voenno-Meditsinskii Zhurnal
|October 8, 2014
Summary
Resistant hypertension affects up to 15% of patients in Russia. A new surgical approach, endovascular renal sympathetic denervation, helps control blood pressure but does not cure hypertension.
Area of Science:
- Cardiology
- Nephrology
- Vascular Surgery
Context:
- Resistant hypertension affects up to 15% of patients in Russia.
- Standard medical treatment requires at least 3 medications, often at maximum doses, including a diuretic.
- Achieving target blood pressure levels may necessitate 4-5 antihypertensive agents.
Purpose:
- To present an algorithm for the diagnosis and treatment of resistant hypertension using a surgical method.
- To evaluate the efficacy of interventional intravascular radio-wave ablation for resistant hypertension.
Summary:
- A novel treatment algorithm for resistant hypertension is proposed, incorporating endovascular renal sympathetic denervation.
- This minimally invasive procedure selectively disrupts sympathetic nervous system connections via radio-wave ablation.
- The method effectively controls arterial blood pressure and optimizes antihypertensive therapy.
Impact:
- Endovascular renal sympathetic denervation offers a new therapeutic option for managing difficult-to-treat hypertension.
- While not a cure, the procedure demonstrates significant potential in improving blood pressure control.
- This approach may reduce the need for complex polypharmacy in resistant hypertension cases.
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