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DNA Microarrays

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

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Related Experiment Video

Updated: Apr 23, 2026

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

Published on: January 30, 2017

Studying bovine early embryo transcriptome by microarray.

Isabelle Dufort¹, Claude Robert, Marc-André Sirard

¹Département des Sciences Animales, Pavillon INAF, Faculté des Sciences de l'Agriculture et de l'Alimentation, Centre de Recherche en Biologie de la Reproduction, Université Laval, local 2732, Pavillon des Services, Québec, QC, Canada, G1V 0A6.

Methods in Molecular Biology (Clifton, N.J.)

|October 8, 2014

Summary

This summary is machine-generated.

Microarray technology enables rapid analysis of numerous genes in early embryo development, even with limited genetic material. The EmbryoGENE Network developed specific protocols for studying the bovine transcriptome using this powerful method.

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Last Updated: Apr 23, 2026

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Published on: January 30, 2017

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Area of Science:

Reproductive Biology
Genomics
Developmental Biology

Background:

Studying gene expression in early embryos is challenging due to limited sample sizes.
Microarrays offer a high-throughput method for analyzing gene expression patterns.

Purpose of the Study:

To describe protocols for bovine early embryo transcriptome analysis using microarrays.
To facilitate large-scale gene expression studies in bovine embryos.

Main Methods:

Development of microarray protocols by the EmbryoGENE Network.
Application of microarray experimental design for bovine embryo samples.

Main Results:

Established protocols for efficient bovine transcriptome analysis.
Demonstrated the utility of microarrays for studying gene expression in early embryos.

Conclusions:

Microarray technology is advantageous for studying the bovine transcriptome in early embryos.
The developed protocols enable comprehensive gene expression profiling in limited embryonic samples.