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Published on: September 3, 2013
Post-treatment MRI aspects of photodynamic therapy for prostate cancer
1Department of Radiology, CHU Angers, 4 rue Larrey, 49100, Angers, France, kulik_melanie@yahoo.fr.
Objectives:
Photodynamic therapy is a new focal therapy for prostate cancer.
Methods:
In this technique, a photosensitising agent is introduced intravenously, then activated by local laser illumination to induce tumour necrosis. Treatment efficacy is assessed by magnetic resonance imaging (MRI).
Results And Conclusions:
We illustrate specific post-treatment MRI aspects at early and late follow-up with pathological correlations.
Teaching Points:
• Dynamic phototherapy is a new and promising focal therapy for prostate cancer. • One-week MRI shows increased volume of the treated lobe and large, homogeneous necrosis area. • Six-month MRI shows significant changes of the prostate shape and signal. • Six-month MRI becomes "base line" appearance for further follow-up or monitoring.
