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Updated: Apr 23, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Early onset of prosthesis failure after aortic valve replacement
D Karangelis1, S Fragoulis2, A Bairaktaris2
1First Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, Athens, Greece dimoskaragel@yahoo.gr.
A 78-year-old man experienced severe aortic regurgitation 3 months after aortic valve replacement with a porcine valve. The prosthetic valve was explanted and replaced with a different model.
Area of Science:
- Cardiology
- Cardiac Surgery
- Biomedical Engineering
Background:
- Aortic stenosis is a common valvular heart disease requiring valve replacement.
- Tissue valves, such as porcine valves, are frequently used for aortic valve replacement.
- Early prosthetic valve dysfunction can lead to significant morbidity and mortality.
Observation:
- A 78-year-old male patient underwent aortic valve replacement with a 21 mm Labcor tissue porcine aortic valve.
- Postoperatively, the patient had an uncomplicated course for 3 months.
- Transthoracic echocardiography revealed restrictive motion of the non-coronary cusp, incomplete coaptation, and severe aortic regurgitation.
Findings:
- The Labcor tissue porcine aortic valve demonstrated early structural dysfunction.
- The observed dysfunction led to severe aortic regurgitation, necessitating reoperation.
- Exploitation of the prosthetic valve and implantation of an alternative model were performed.
Implications:
- This case highlights the potential for early structural valve deterioration in tissue prostheses.
- It underscores the importance of vigilant echocardiographic monitoring after aortic valve replacement.
- Further research into the long-term durability and failure modes of specific tissue valve models is warranted.
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