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Updated: Apr 22, 2026

Inoculation Strategies to Infect Plant Roots with Soil-Borne Microorganisms
Published on: March 1, 2022
Induced systemic resistance and the rhizosphere microbiome.
Peter A H M Bakker1, Rogier F Doornbos1, Christos Zamioudis1
1Plant-Microbe Interactions, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands.
Plant root microbiomes protect plants from disease, particularly in suppressive soils. Induced systemic resistance (ISR) is a key mechanism, influencing both plant defense and the wider rhizosphere microbiome.
Area of Science:
- Plant Pathology
- Microbiology
- Soil Science
Background:
- Plant roots host diverse microbial communities, forming the rhizosphere microbiome.
- This microbiome significantly influences plant health and disease resistance.
- Disease suppressive soils exhibit enhanced protection against plant pathogens.
Purpose of the Study:
- To explore the role of the plant root microbiome in disease suppression.
- To investigate the mechanisms of disease suppression, focusing on induced systemic resistance (ISR).
- To discuss the implications of ISR on the composition and function of the rhizosphere microbiome.
Main Methods:
- Literature review on plant-microbe interactions and disease suppression mechanisms.
- Analysis of studies investigating induced systemic resistance (ISR) in biological control.
- Discussion of the interplay between ISR and rhizosphere microbiome dynamics.
Main Results:
- The plant root microbiome plays a crucial role in plant health and disease suppression.
- Induced systemic resistance (ISR) is a significant mechanism contributing to disease suppression, often mediated by beneficial microbes.
- ISR influences the recruitment and activity of microorganisms within the rhizosphere.
Conclusions:
- The plant root microbiome is vital for plant health and disease resistance.
- Induced systemic resistance (ISR) is a key mechanism underlying biological control of plant diseases.
- Understanding ISR's impact on the rhizosphere microbiome is essential for developing sustainable agricultural practices.
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