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Updated: Apr 22, 2026
Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
Published on: June 7, 2020
Evaluation of Thiel cadaveric model for MRI-guided stereotactic procedures in neurosurgery
Sam Eljamel1, Alexander Volovick2, Timur Saliev1
1Centre for Neurosciences, College of Medicine, Dentistry and Nursing, Ninewells Hospital and Medical School, Dundee, UK.
Background:
Magnetic resonance imaging (MRI)-guided deep brain stimulation (DBS) and high frequency focused ultrasound (FUS) is an emerging modality to treat several neurological disorders of the brain. Developing reliable models to train and assess future neurosurgeons is paramount to ensure safety and adequate training of neurosurgeons of the future.
Methods:
We evaluated the use of Thiel cadaveric model to practice MRI-guided DBS implantation and high frequency MRI-guided FUS in the human brain. We performed three training sessions for DBS and five sonications using high frequency MRI-guided FUS in five consecutive cadavers to assess the suitability of this model to use in training for stereotactic functional procedures.
Results:
We found the brains of these cadavers preserved in an excellent anatomical condition up to 15 months after embalmment and they were excellent model to use, MRI-guided DBS implantation and FUS produced the desired lesions accurately and precisely in these cadaveric brains.
Conclusion:
Thiel cadavers provided a very good model to perform these procedures and a potential model to train and assess neurosurgeons of the future.
