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Updated: Apr 22, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis
Published on: July 8, 2025
A case of microstomia subsequent to toxic epidermal necrolysis surgically treated by simple technique
Takanobu Mashiko1, Toshiharu Minabe1, Aiko Oka1
1Department of Plastic Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; and Department of Plastic Surgery, University of Tokyo School of Medicine, Tokyo, Japan.
Summary:
Toxic epidermal necrolysis (TEN) is a rare but severe adverse dermatitis that is an autoimmune reaction to drugs such as nonsteroidal anti-inflammatory drugs. TEN most severely affects the mucous membranes including the mouth and could develop into microstomia; however, microstomia in relation to TEN has rarely been reported in the literature. We describe an adult female patient who developed microstomia due to scar contracture of the bilateral oral commissures subsequent to TEN and was successfully treated by a simple surgical technique consisting solely of transverse incision of the commissure and longitudinal closure.

