Related Experiment Video

Updated: Aug 17, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

Total lymphoid irradiation

S Slavin1

  • 1Department of Bone Marrow Transplantation and Immunobiology Research, Hadassah University Hospital, 91120 Jerusalem, Israel.

Immunology Today
|October 8, 2014
PubMed

The delivery of ionizing radiation to lymph nodes, thymus and spleen while non-lymphoid organs are shielded has profoundly immunosuppressive effects that may have value in transplantation and the treatment of autoimmune disorders. Here Shimon Slavin reviews what is known of the cellular consequences of total lymphoid irradiation in animals and discusses the results of its use in various clinical immunosuppressive treatment regimens.

More Related Videos

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma09:10

An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma

Published on: November 15, 2024

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.