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"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM
Published on: August 26, 2016
Surface carbohydrates and surface lectins are recognition determinants in phagocytosis
1Department of Biophysics, The Weizmann Institute of Science, Rehovot 76100, Israel.
Abstract:
Phagocytic cells constantly come into contact with various cells and particulate materials, yet in the absence of antibody they attach to and ingest only some of them. The molecular basis for this selective recognition, discussed here by Nathan Sharon, seems on recent evidence to lie in interactions between lectins and sugars on the surface of the phagocytes and the particles they engulf.
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