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Factor-induced differentiation and activation of macrophages
1Macrophage Laboratory of the Imperial Cancer Research Fund, Lincoln's Inn Fields, London WC2A 3PX, UK.
Immunology Today
|October 8, 2014
Abstract:
The cells of the mononuclear phagocyte lineage, namely monocytes and macrophages secrete over 50 proteins. This impressive versatility is regulated both internally, during the cells' maturation, and by events in the extracellular environment which activate the cells. Differentiation and activation are profoundly influenced by a variety of cytokines and these interactions were among the themes of a recently reported meeting.

