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Updated: Apr 22, 2026
An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur
Published on: October 23, 2017
Effects of laser vs ultrasound on bone healing after distraction osteogenesis: A histomorphometric analysis
Myrla Alves Barros Medeiros1, Leonard Euler Andrade Gomes Nascimento2, Thiago Chon Leon Lau3
1a Student, Department of Orthodontics, Universidade Federal do Piauí, UFPI, Teresina, Piauí, Brazil.
Objective:
To assess the effects of low-level laser irradiation vs ultrasound irradiation on bone healing after distraction osteogenesis.
Materials And Methods:
Distraction osteogenesis was performed with rapid maxillary expansion devices (Hyrax-Morelli, Sorocaba, São Paulo Brazil) in 24 rabbits (Oryctolagus cuniculus). After a 2-day latency period, the distraction devices were activated for 10 days at a rate of 1 mm/d. Four groups of six animals were treated as follows: (1) control, (2) laser irradiation on the right side, (3) ultrasound irradiation on the right side, and (4) laser irradiation on the right side and ultrasound on the left side. Histomorphometric analysis was used to assess the bone healing area. Analysis of variance was used to perform the statistical analyses.
Results:
The influence of low-intensity laser associated with ultrasound irradiation on bone healing was statistically significant. The analyses showed the greatest amount of bone healing in the jaws of animals in group 4, which received treatment with both ultrasound and laser.
Conclusion:
This study concluded that bone healing is accelerated with the application of laser irradiation. The greatest effects were observed with combined ultrasound and laser treatment.
