Related Experiment Video
Updated: Apr 22, 2026

In Vivo Immunofluorescence Localization for Assessment of Therapeutic and Diagnostic Antibody Biodistribution in Cancer Research
Published on: September 16, 2019
Limiting factors in the localization of tumours with radiolabelled antibodies
A R Bradwell1, D S Fairweather2, P W Dykes3
1Immuno Diagnostic Research Laboratory, Department of Immunology, The Medical School, University of Birmingham. B15 2TJ, UK.
Abstract:
The use of radiolabelled antibodies in tumour detection is being intensely studied. Here A. R. Bradwell and colleagues discuss the use of radioimmunolocation and conclude that although many different tumour types can be localized, results at present are no better than with otherscanning techniques. Dramatic improvements will depend upon afuller understanding of tumour cell biology and the optimization of all the parameters that contribute to successful scans.

