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Diabetes Mellitus: Type 2 and Gestational01:22

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Type I Diabetes II: Pathophysiology01:26

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Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular...
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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
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Improving IV Insulin Administration in a Community Hospital
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Shift work and diabetes--a systematic review.

Anders Knutsson1, Anders Kempe

  • 1Department of Health Sciences, Mid Sweden University , Sundsvall , Sweden and.

Chronobiology International
|October 8, 2014
PubMed
Summary
This summary is machine-generated.

Shift work, increasingly common globally, is a potential risk factor for type 2 diabetes. This review examines the association between shift work and type 2 diabetes (T2D) and its management.

Keywords:
Circadian disruptiondiabetes controlnightworkshiftworkwork schedules

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Area of Science:

  • Endocrinology
  • Occupational Health
  • Public Health

Background:

  • Diabetes mellitus is a growing global health concern, with type 2 diabetes (T2D) accounting for 90% of cases.
  • T2D is linked to insulin resistance and weight gain.
  • The prevalence of shift work is increasing, raising concerns about its potential impact on public health.

Purpose of the Study:

  • To systematically review the scientific literature on the association between shift work and T2D.
  • To explore existing research on managing diabetes in individuals who perform shift work.

Main Methods:

  • Systematic literature review.
  • Analysis of epidemiological studies and clinical research.
  • Synthesis of evidence on risk factors and management strategies.

Main Results:

  • Evidence suggests a potential association between shift work and an increased risk of developing T2D.
  • Shift work may exacerbate insulin resistance and contribute to metabolic dysfunction.
  • Management strategies for diabetic shift workers require further investigation.

Conclusions:

  • Shift work represents a significant occupational risk factor for T2D.
  • Further research is needed to elucidate the mechanisms and develop targeted interventions for shift workers with diabetes.