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Updated: Apr 22, 2026

Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood
Published on: February 6, 2018
The surface antigens of human B lymphocytes
1Department of Clinical Immunology, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia.
Abstract:
During the past few years identification and characterization of the surface antigens of B lymphocytes using monoclonal antibodies has continued apace. International Workshops on Leucocyte Differentiation Antigens have categorized many antibodies using the cluster of differentiation (CD) system. Here Heddy Zola reviews the recent advances in antigen identification - including those defined by unclustered antibodies as well as CD antigens - and indicates that the bulk of future work will revolve around attempts to place them within a functional framework.
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