Anti-idiotypic antibodies: what do they recognize?
1Department of Microbiology, Cancer Center/Institute of Cancer Research, Columbia University, New York, NY 10032, USA.
Abstract:
On the basis of our present comprehension of the structure of ligand-binding proteins, B. F. Erlanger here discusses how anti-idiotypic antibodies react with their target epitopes, in particular, when anti-idiotypic antibodies cross-react with receptors or act as internal images of ligands.
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