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Hybridomas from unimmunized individuals

Y Shoenfeld1, I P Witz2

  • 1Research Unit of Autoimmune Diseases, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.

Immunology Today
|October 8, 2014
PubMed

The products of hybridomas are widely used to define and characterize markers for diagnostic or therapeutic purposes. Little attention has been paid to the value of hybridoma products originating from the immunocytes of animals on people who have not been artificially immunized. At a recent French-Israeli meeting on this theme∗, discussion focused on the analysis of natural autoantibodies and their role in autoimmunity, natural anti-tumor antibodies, and hybrids formed between somatic host cells and tumor cells.

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