Natural selection: it's a many-small world after all
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Updated: Apr 22, 2026

Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli
Published on: March 16, 2011
Marius Roesti1, Walter Salzburger1
1Zoological Institute, University of Basel, Vesalgasse 1, 4051 Basel, Switzerland.
Abstract:
Understanding adaptive phenotypic change and its genetic underpinnings is a major challenge in biology. Threespine stickleback fish, experimentally exposed to divergent semi-natural environments, reveal that adaptive diversification can happen readily, affects many traits and involves numerous genetic loci across the genome.
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