Related Experiment Video
Updated: Sep 13, 2026

Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model
Published on: February 28, 2014
[Treatment of tubal pregnancy with methotrexate]
A Chryssikopulos1, O Grigoriu, N Vitoratos
1Universitätsklinik für Geburtsheilfe und Frauenheilkunde (Aretaiion-Hospital), Athen, Griechenland.
Abstract:
Three women with unruptured tubal pregnancy, confirmed by laparoscopy were treated with a total dose of 140 mg methotrexate. The medicament was given in two therapeutic cycles. The action of methotrexate in the trophoblastic tissue was evaluated by serial determinations of beta hCG. No side effects were observed during the treatment. When the level of beta hCG dropped to 10 mIU/ml, the entire ectopic foetus (including the amnion, membrane, trophoderm and all pertaining tissue and fluids) was removed through the tube by massage after minilaparotomy. The patency of tubes proved to be normal on performing postoperative hysterosalpingography. One of the three patients delivered a healthy baby, another is in the third trimester of a normal pregnancy.
More Related Videos
Related Concept Videos
Drugs that Stabilize Microtubules
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Ovarian Cycle
Birth Control Methods

