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Differences in the corneal biomechanical changes after SMILE and LASIK
Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|October 8, 2014
Summary
Small Incision Lenticule Extraction (SMILE) and LASIK both alter corneal biomechanics. SMILE shows less impact on corneal hysteresis and resistance factor in high myopia compared to LASIK.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Biomechanical Analysis
Background:
- Refractive surgery aims to correct vision by reshaping the cornea.
- Small Incision Lenticule Extraction (SMILE) and Femtosecond Laser-Assisted In Situ Keratomileusis (LASIK) are popular laser vision correction procedures.
- Understanding the biomechanical changes induced by these procedures is crucial for patient safety and outcomes.
Purpose of the Study:
- To compare the effects of SMILE and LASIK on corneal biomechanical properties.
- To evaluate these changes in different levels of myopia.
- To utilize the Ocular Response Analyzer for precise measurements.
Main Methods:
- 187 eyes (SMILE) and 79 eyes (LASIK) were analyzed.
- Patients were grouped by surgery type and myopia severity (≤ -6.00 D or > -6.00 D).
- Corneal hysteresis, corneal resistance factor, and waveform parameters were measured preoperatively and postoperatively.
Main Results:
- Both SMILE and LASIK caused significant decreases in corneal hysteresis and resistance factor.
- In low myopia (≤ -6.00 D), no significant differences were observed between SMILE and LASIK.
- In high myopia (> -6.00 D), LASIK resulted in a significantly greater decrease in corneal hysteresis and resistance factor compared to SMILE.
Conclusions:
- SMILE demonstrates a less pronounced impact on corneal biomechanical properties, specifically hysteresis and resistance factor, in patients with high myopia compared to LASIK.
- These findings suggest potential advantages for SMILE in preserving corneal integrity in higher myopic corrections.

