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Childhood cancer incidence and survival 1985-2009, Khon Kaen, Thailand

Surapon Wiangnon1, Arunee Jetsrisuparb, Patcharee Komvilaisak

  • 1Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand

Asian Pacific Journal of Cancer Prevention : APJCP
|October 9, 2014
PubMed

Insights

Childhood cancer incidence in Khon Kaen is lower than in Western countries. Survival rates for several childhood cancers, including acute lymphoblastic leukemia and lymphoma, are also lower, though some, like CNS tumors, are comparable.

Area of Science:

  • Pediatric Oncology
  • Cancer Epidemiology
  • Public Health

Background:

  • The Khon Kaen Cancer Registry (KKCR) was established in 1984 to track childhood cancer.
  • Previous studies had limited registration periods, necessitating a comprehensive analysis.

Purpose of the Study:

  • To determine the incidence and survival rates of childhood cancer in Khon Kaen, Thailand.
  • To provide updated statistics for childhood cancer based on a longer registration period.

Main Methods:

  • Utilized KKCR data for children aged 0-15 years diagnosed with cancer between 1985-2009.
  • Classified cancers using the International Classification of Childhood Cancer and calculated incidence and survival using standard methods and Kaplan Meier analysis.
  • Follow-up extended to December 31, 2012.

Main Results:

  • Registered 912 childhood cancer cases, with an age-standardized rate of 83 per million.
  • Leukemia was the most common cancer (33.8 per million), followed by CNS tumors (12.8 per million) and lymphoma (7.0 per million).
  • The 5-year overall survival for all childhood cancers was 52%, with significant variation among specific cancer types.

Conclusions:

  • Childhood cancer incidence in Khon Kaen is lower compared to Western countries.
  • Survival rates for acute lymphoblastic leukemia, lymphoma, renal tumors, liver tumors, retinoblastoma, and soft tissue tumors are lower than in developed nations.
  • Survival for central nervous system tumors, neuroblastoma, and germ cell tumors is comparable to developed countries.
Abstract

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