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Published on: December 4, 2020
[Prophylaxis of recurrent urinary tract infections]
W Vahlensieck1, H-W Bauer, H J Piechota
1Fachklinik Urologie, Kurpark-Klinik, Kurstraße 41-45, 61231, Bad Nauheim, Deutschland, drvahlensieck@kurpark-klinik.com.
Recurrent urinary tract infections (rUTIs) can be reduced with established treatments like antibiotic prophylaxis and immunotherapy. Emerging options such as estriol and cranberry supplements show promise for preventing rUTIs.
Area of Science:
- Urology
- Infectious Diseases
- Pharmacology
Context:
- Recurrent urinary tract infections (rUTIs) significantly impact women's quality of life, with few treatable predisposing factors.
- Established prevention strategies include general recommendations and antibiotic prophylaxis, reducing recurrence rates.
- Current European Association of Urology guidelines prioritize specific antibiotics and restrict others for rUTI management.
Purpose:
- To review current and emerging strategies for the prevention of recurrent urinary tract infections (rUTIs).
- To evaluate the efficacy and safety of various prophylactic treatments for rUTIs.
- To discuss the role of antibiotics, immunotherapy, and novel approaches in managing rUTI recurrence.
Summary:
- General recommendations and antibiotic prophylaxis (long-term or postcoital) are effective, lowering rUTI recurrence rates.
- Oral and parenteral immunotherapy have demonstrated efficacy in preventing rUTIs, often complementing antibiotic therapy.
- Vaginal estriol prophylaxis shows positive effects with minimal side effects; cranberry supplements also show promise for rUTI prevention.
Impact:
- Provides a comprehensive overview of rUTI prevention strategies, aiding clinical decision-making.
- Highlights the effectiveness of established treatments and the potential of novel therapies like estriol and cranberry.
- Informs healthcare providers about evidence-based and emerging options to improve patient outcomes for recurrent UTIs.
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