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[Ambulatory myelography using iohexol (Omnipaque): methods and results]
Abstract:
Outpatient myelography with iohexol (Omnipaque) was performed in 150 patients. Side effects were noted in 28 patients (19%), with only 3 (2%) major complaints. It concerned 2 patients with severe and prolonged headache and one patient with seizures. Side effects were not more frequent in outpatient myelography than in reported series of hospitalized patients. The frequency of side effects was significantly lower with the use of iohexol than in comparable studies with metrizamide. Headache was the most frequent side effect, followed by an increase or exacerbation of ischiatiform pain, nausea and vomiting. Side effects were slightly more frequent in cervical myelography than in lumbar myelography and were not related to underlying pathology. It is concluded that outpatient myelography is feasable for as far as iohexol is used and patient surveillance is carefully organized.
Insights
Outpatient myelography using iohexol is safe and effective, with a low rate of side effects (19%) compared to older agents like metrizamide. This procedure is feasible when iohexol is used and patient surveillance is well-organized.
Area of Science:
- Radiology
- Neurology
- Medical Imaging
Background:
- Myelography is a diagnostic imaging procedure.
- Previous studies reported varying side effect profiles with different contrast agents.
Purpose of the Study:
- To evaluate the safety and feasibility of outpatient myelography using iohexol (Omnipaque).
Main Methods:
- Outpatient myelography was performed in 150 patients using iohexol.
- Adverse events were systematically recorded and analyzed.
Main Results:
- 19% of patients experienced side effects, with only 2% reporting major complaints (headache, seizures).
- Side effect rates were comparable to hospitalized patients and significantly lower than with metrizamide.
- Headache was the most common side effect, followed by ischiatiform pain, nausea, and vomiting.
Conclusions:
- Outpatient myelography with iohexol is a feasible procedure.
- Careful patient surveillance is crucial for successful outpatient myelography.