High-throughput gene expression profiling of opioid-induced alterations in discrete brain areas
Michal Korostynski1, Marcin Piechota, Slawomir Golda
1Department of Molecular Neuropharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31343, Krakow, Poland.
Methods in Molecular Biology (Clifton, N.J.)
|October 9, 2014
Abstract:
Whole-genome screening methods are unique approach to search for novel genes and molecular pathways involved in drug action. High-throughput profiling allows the gene expression levels of tens of thousands of transcripts to be measured simultaneously. Here, we describe transcriptional profiling in a specific area of the brain using DNA microarrays and next-generation sequencing.
