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Does surgically induced right bundle branch block really effect ventricular function in children after ventricular
Cem Karadeniz1, Semra Atalay, Fikri Demir
1Departmet of Pediatric Cardiology, School of Medicine, Ankara University, Cebeci, 06620, Ankara, Turkey, karadenizcem@yahoo.com.
Insights
Right bundle branch block (RBBB) may indicate right ventricular dysfunction in patients after surgical ventricular septal defect (VSD) repair. Biventricular dysfunction can occur post-VSD repair, with tissue Doppler imaging detecting subclinical issues.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Echocardiography
Background:
- Surgical repair of ventricular septal defects (VSD) is common.
- Right bundle branch block (RBBB) can occur after VSD repair.
- Long-term effects on biventricular function require further investigation.
Purpose of the Study:
- To assess left and right ventricular function in patients with repaired VSD.
- To investigate the impact of RBBB on ventricular function post-VSD repair.
- To compare ventricular function in operated patients with and without RBBB against healthy controls.
Main Methods:
- Prospective study including 53 patients with repaired VSD and 52 healthy controls.
- Electrocardiography and conventional/tissue Doppler echocardiography were performed.
- Comparison of echocardiographic parameters between groups: VSD repair with RBBB, VSD repair without RBBB, and controls.
Main Results:
- RBBB detected in 37.7% of operated patients.
- Patients with RBBB showed decreased right ventricular fractional area change.
- Operated patients exhibited impaired systolic and diastolic function (tricuspid annular plane systolic excursion, myocardial velocities) and elevated myocardial performance indices compared to controls, irrespective of RBBB.
Conclusions:
- RBBB may be associated with right ventricular dysfunction following surgical VSD repair.
- Biventricular systolic and diastolic dysfunction can develop post-VSD repair, even without RBBB.
- Tissue Doppler echocardiography is valuable for detecting subclinical biventricular dysfunction in these patients.
Abstract:
In this prospective study, we aimed to assess left and right ventricular function in terms of the presence of right bundle branch block (RBBB) in the cases with repaired ventricular septal defect (VSD). Fifty-three patients who had VSD surgery at least 1-year preceding admission and 52 healthy controls were enrolled into the study. All the participants underwent electrocardiographic and echocardiographic examination. The cases with RBBB were determined. The conventional and tissue Doppler echocardiographic measurements of the patients with and without RBBB were compared with each other and healthy controls. Twenty-eight of VSD repair groups were male and 25 were female. Control group consisted of 30 males and 22 females. The mean age of the study and control groups was 7.5 ± 5.0 and 6.9 ± 4.3 years, respectively. RBBB was detected in 20 of 53 (37.7 %) operated patients. The only significant difference between the cases with and without RBBB was decreased right ventricular fractional area change (%) in the former group (33 ± 7 vs. 39 ± 5 p < 0.05). When compared to controls, operated group had statistically lower [corrected] tricuspid annular plane systolic excursion (p < 0.05), lower systolic, early diastolic, and late diastolic myocardial velocities, higher left and right ventricular myocardial performance indices, irrespective of the presence of RBBB. The ratios of mitral or tricuspid inflow to left or right ventricular myocardial in early diastolic velocities measured from lateral annular levels were increased in operated group (all p values <0.05). In conclusion, RBBB in the cases with surgical VSD repair might be associated with right ventricular dysfunction. Biventricular systolic and diastolic dysfunction may develop following VSD repair irrespective of the presence of RBBB. Tissue Doppler-derived myocardial performance indices are useful in detection of those subclinical dysfunctions.
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