Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prevalence and disease trajectories of pulmonary fibrosis of childhood interstitial lung disease: a register-based, multicentre observational study.

The Lancet. Respiratory medicine·2026

Same author

Malnutrition in childhood interstitial lung diseases is associated with reduced lung function and greater disease severity: insights from the chILD-EU registry.

Respiratory medicine·2026

Same author

AK8 deficiency causes primary ciliary dyskinesia by disrupting energy homeostasis in the airways.

American journal of respiratory and critical care medicine·2026

Same author

Management and Long-Term Outcomes of Persistent Tachypnea of Infancy/Neuroendocrine Cell Hyperplasia of Infancy: A European Multicenter Retrospective Study.

Chest·2026

Same author

Incidence of Esophageal Atresia and Associated Respiratory Morbidity in Children: A National Registry Study in Denmark (1998-2018).

Pediatric pulmonology·2026

Same author

Mental Health in a Diverse Group of Children, Adolescents, and Adults Previously Treated for Childhood Interstitial Lung Disease.

Pediatric pulmonology·2025

Search research articles

Related Experiment Video

Updated: Apr 22, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

[Diffuse lung disease in children].

Frederik Buchvald¹, Kim G Nielsen

¹Dansk BørneLunge Center, BørneUnge-Klinikken, Rigshospitalet, Blegdamsvej 9, 2100 København Ø. fbuchvald@dadlnet.dk.

Ugeskrift for Laeger

|October 9, 2014

Summary

This summary is machine-generated.

Pediatric diffuse lung disease, characterized by breathing difficulties and poor growth, requires specialized care. Advances in genetics and classification aid in understanding and managing these rare, serious childhood respiratory conditions.

More Related Videos

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Direct Intrabronchial Administration to Improve the Selective Agent Deposition Within the Mouse Lung

Direct Intrabronchial Administration to Improve the Selective Agent Deposition Within the Mouse Lung

Published on: May 20, 2019

Related Experiment Videos

Last Updated: Apr 22, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Direct Intrabronchial Administration to Improve the Selective Agent Deposition Within the Mouse Lung

Direct Intrabronchial Administration to Improve the Selective Agent Deposition Within the Mouse Lung

Published on: May 20, 2019

Area of Science:

Pediatric Pulmonology
Respiratory Medicine
Medical Genetics

Context:

Diffuse lung disease in children presents significant morbidity and mortality.
Common symptoms include tachypnea and failure to thrive.
Radiological and histopathological abnormalities are characteristic.

Purpose:

To review the current understanding of pediatric diffuse lung diseases.
To highlight the challenges in diagnosis and management.
To emphasize the need for specialized, interdisciplinary care.

Summary:

Recent advances in genetics and pathophysiology have improved understanding.
A new pediatric classification aids in diagnosis.
Management is complex, requiring a centralized, interdisciplinary approach.

Impact:

Improved diagnostic and management strategies for rare pediatric lung diseases.
Enhanced understanding of the genetic and pathophysiological basis.
Facilitation of early intervention and better patient outcomes through specialized centers.