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Updated: Apr 22, 2026

Measuring Membrane Lipid Turnover with the pH-sensitive Fluorescent Lipid Analog ND6
Published on: July 29, 2021
A naphthalimide-based fluorescence "turn-on" probe for the detection of Pb(2+) in aqueous solution and living cells
Hio-Ieng Un1, Chang-Bo Huang, Junhai Huang
1Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai (China).
Abstract:
An easily available naphthalimide-based fluorescent probe NPA for Pb(2+) detection was successfully developed. NPA exhibited an obvious fluorescence turn-on response toward Pb(2+) in aqueous solution and in living cells. Moreover, a series of model compounds were rationally designed and synthesized in order to explore the sensing mechanism and binding mode of NPA with Pb(2+) .
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