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Updated: Apr 22, 2026

Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
Published on: April 28, 2013
Cardiac imaging for the assessment of patients being evaluated for kidney or liver transplantation
Kalindi Parikh1, Andrew Appis, Rami Doukky
1Division of Cardiology, Rush University Medical Center, Chicago, IL, USA.
Insights
Assessing cardiac risk before kidney and liver transplants is key. This review examines coronary artery disease in transplant candidates and the role of noninvasive cardiac imaging for risk evaluation.
Area of Science:
- Cardiology
- Transplant Medicine
- Medical Imaging
Background:
- Cardiac risk assessment before kidney and liver transplantation remains controversial.
- Selecting transplant recipients with favorable cardiovascular profiles is crucial due to organ scarcity.
- Noninvasive cardiac imaging for guiding cardiovascular risk assessment in these patients presents challenges.
Purpose of the Study:
- To address the prevalence of coronary artery disease in kidney and liver transplant candidates.
- To review the diagnostic accuracy of noninvasive cardiac imaging techniques in this population.
- To evaluate the prognostic value of these imaging techniques for transplant candidates.
Main Methods:
- Literature review of studies on cardiac risk assessment in transplant candidates.
- Analysis of diagnostic accuracy of noninvasive cardiac imaging.
- Evaluation of prognostic value of cardiac imaging techniques.
Main Results:
- Coronary artery disease is a significant concern in kidney and liver transplant candidates.
- Noninvasive cardiac imaging techniques show variable diagnostic accuracy and prognostic value.
- Evidence synthesis on the utility of imaging in risk stratification.
Conclusions:
- Further research is needed to optimize cardiac risk assessment in transplant candidates.
- Noninvasive cardiac imaging plays a role, but its application requires careful consideration.
- Improved risk stratification can enhance outcomes for kidney and liver transplant recipients.
Abstract:
Cardiac risk assessment prior to kidney and liver transplantation is controversial. Given the paucity of available organs, selecting appropriate recipients with favorable short- and long-term cardiovascular risk profile is crucial. Using noninvasive cardiac imaging tools to guide cardiovascular risk assessment and management can also be challenging and controversial. In this article, we address the burden of coronary artery disease among kidney and liver transplant candidates and review the literature pertaining to the diagnostic accuracy and the prognostic value of noninvasive cardiac imaging techniques in this population.
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