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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma I: Introduction01:28

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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

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Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Antiasthma Drugs: Muscarinic Receptor Antagonists01:20

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Muscarinic receptor antagonists, also known as antimuscarinic agents, are a class of bronchodilators used to treat asthma, although they are more commonly used to treat COPD. They work by inhibiting the action of acetylcholine (ACh), a neurotransmitter, on muscarinic receptors found in the airways.
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Related Experiment Video

Updated: Apr 22, 2026

Murine Model of Allergen Induced Asthma
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[Asthma among mink workers].

Berit Grøntved1, Ole Carstensen, Rolf Petersen

  • 1Arbejdsmedicinsk Klinik, Slagelse Sygehus, Ingemannsvej 18, 4200 Slagelse.

Ugeskrift for Laeger
|October 9, 2014
PubMed
Summary

Two cases of asthma in mink workers suggest a higher risk. One farmer showed allergy to mink urine, while another worker experienced asthma when handling mink furs, indicating occupational asthma potential.

Area of Science:

  • Occupational health
  • Pulmonary medicine
  • Veterinary science

Background:

  • Asthma is a chronic respiratory condition affecting millions globally.
  • Occupational asthma is triggered by workplace exposures, often leading to significant morbidity.
  • Mink farming involves close contact with animals and their byproducts, posing potential respiratory risks.

Observation:

  • A mink farmer with difficult-to-treat asthma showed a positive histamine release test to mink urine.
  • A mink farm worker experienced an asthma attack specifically when handling mink furs.
  • Peak flow monitoring indicated a work-related asthma pattern in the second case, despite no clear allergic markers.

Findings:

  • The presented cases suggest a potential link between mink farming and the development of asthma.

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  • Exposure to mink urine and handling mink furs may act as occupational asthma triggers.
  • Diagnostic challenges exist, as allergic sensitization is not always evident in occupational asthma.

    • Implications:

    • These findings highlight the need for increased awareness of occupational asthma risks in the mink farming industry.
    • Further research is warranted to elucidate the specific allergens and mechanisms involved.
    • Implementing workplace safety measures may be crucial for preventing asthma in mink workers.