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Updated: Apr 22, 2026

SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs
Published on: June 28, 2019
[Drug safety: challenge in an aging society]
M Huber1, A Blumberg, S Chatterjee
1Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Deutschland, martin.huber@bfarm.de.
Elderly patients take more medications, increasing drug safety risks. Reporting adverse drug reactions by physicians improves data for safer prescribing in older adults.
Area of Science:
- Geriatric Pharmacology
- Pharmacovigilance
- Public Health
Context:
- Increasing elderly population globally.
- High prevalence of multimorbidity and polypharmacy in older adults.
- Critical need for drug safety in the elderly population.
Purpose:
- To highlight the importance of drug safety in the elderly.
- To emphasize the role of spontaneous reporting in improving drug safety data.
- To introduce the AgeCoDe study for longitudinal drug safety research.
Summary:
- Limited data exists on medication risks for the elderly.
- Spontaneous reporting of adverse drug reactions (ADRs) is crucial for enhancing knowledge.
- Physicians' accurate reporting significantly improves pharmacovigilance effectiveness.
Impact:
- Enhances understanding of drug risks in aging populations.
- Supports regulatory assessments and recommendations for medication use in the elderly.
- Facilitates evidence-based prescribing practices for improved patient outcomes.
Related Concept Videos
Drug Dosing: Geriatric Patients
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

