Related Experiment Video
Updated: Apr 22, 2026

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue
Published on: July 9, 2014
Diagnosis and treatment of cytomegalovirus 2013
Hermann Einsele1, Stephan Mielke, Götz Ulrich Grigoleit
1Department of Medicine II, Wuerzburg University Medical Center, Wuerzburg, Germany.
Purpose Of Review:
Despite significant improvements in the management of patients undergoing allogeneic stem cell transplantation, including anticytomegalovirus (CMV) prophylaxis and treatment, clinical handling of CMV infection remains challenging in the light of high morbidity and mortality rates. Thus, novel strategies and agents to control CMV infection and disease will be discussed.
Recent Findings:
Novel assays to quantify viral load and detect antiviral resistance mechanisms on the basis of next-generation sequencing have been described and will help to earlier and more effectively control CMV infection. In addition, safer and more effective antiviral agents are now available and strategies to boost the CMV-directed immune responses are being explored in the clinic.
Summary:
Novel diagnostic tests, novel agents and the increased understanding of the immune response to CMV have and will have a major impact on improving the management of CMV infection in hematological patients.
More Related Videos
05:53Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
10:24Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System
Published on: October 5, 2015
Related Concept Videos
Cytomegalovirus Disease
Myocarditis III: Medical Management
Cystic Fibrosis: Management
Sinus disease and chronic...
Acute Pyelonephritis II: Diagnostic Studies and Management
Endocarditis III: Medical Management