[Immunoregulatory disorders and the proliferative activity of T- and B-lymphocytes in osteoarthrosis]

The authors studied the activity of nuclear chromatin of the peripheral T- and B-lymphocytes in the polyclonal activation test using the method of quantitative cytofluorometry. A new experimental model in vitro has been proposed for the study of regulatory function of T-lymphocytes. It was found out that in approximately 50% of osteoarthrosis patients the greater part of the peripheral lymphoid population is in the state of initial activation and the activated B-lymphocytes occur more frequently than T-lymphocytes.