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Synthesis and 5HT-receptors affinity of some 4-phenylquinoline derivatives
M Anzini1, S Vomero, A Garofalo
1Dipartimento Farmaco Chimico Tecnologico, Università di Siena, Italy.
Abstract:
The synthesis of a series of 4-phenylquinolines with substituents in 2,3 and 6-position of the quinoline nucleus is described. Serotoninergic activity towards 5HT1A, 5HT1B, 5HT2, 5HT1A + B receptors and the 5-HT-uptake site was also studied.