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The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
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Related Experiment Video

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Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
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Normal reference ranges for left ventricular dimensions in preterm infants.

Lulu Abushaban1, Mariappa Thinakar Vel2, Jebaraj Rathinasamy2

  • 1Department of Pediatric Cardiology, Chest Diseases Hospital, Ministry of Health, Kuwait University, Kuwait ; Department of Pediatric Cardiology, Faculty of Medicine, Ministry of Health, Kuwait.

Annals of Pediatric Cardiology
|October 10, 2014
PubMed
Summary

This study establishes normal reference ranges for left ventricular dimensions in preterm infants. These measurements significantly correlate with gestational age and body weight, providing a crucial tool for clinical assessment.

Keywords:
Body weightchronological agegestational ageleft ventricular dimensionspreterm infants babiesreference ranges

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Area of Science:

  • Neonatal cardiology
  • Pediatric echocardiography
  • Fetal and neonatal physiology

Background:

  • Accurate assessment of cardiac function in preterm infants is critical for optimal management.
  • Establishing normative data for left ventricular dimensions is essential for identifying abnormalities.

Purpose of the Study:

  • To determine normal reference ranges for left ventricular dimensions in preterm infants.
  • To investigate the correlation between these dimensions and gestational age, body weight, and chronological age.

Main Methods:

  • Prospective study of 268 preterm infants in Kuwait (2008-2010).
  • Echocardiograms performed within the first week of life and weekly until 36 weeks' gestation.
  • Left ventricular dimensions measured and correlated with gestational age and body weight categories.

Main Results:

  • All left ventricular measurements showed significant correlation with body weight (P < 0.001) and gestational age.
  • A gradual increase in dimensions was observed with increasing body weight and during the first nine weeks of life.
  • The rate of increase in dimensions slowed after five weeks of life relative to gestational age.

Conclusions:

  • Left ventricular dimensions in preterm infants are significantly influenced by gestational age and body weight.
  • The study provides essential reference data for evaluating left ventricular dimensions in preterm infants.
  • This data serves as a normal reference tool for clinical use in assessing preterm infant cardiac health.