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Updated: Apr 22, 2026

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
Published on: August 31, 2022
An unusual case of primary hepatic lymphoma mimicking sarcoidosis in MRI
Thuy D Do1, Claus Neurohr2, Marlies Michl3
1Department of Clinical Radiology and Interventional Medicine, Heidelberg University, Heidelberg, Germany ; Department of Clinical Radiology, Ludwig Maximilians-University, Munich, Germany.
Abstract:
Sarcoidosis is a granulomatous disease, in which liver affection is common, contrary to a primary hepatic lymphoma that is very rarely seen. On MRI both present with almost the same imaging features: hypointense in T1-weighted and hyperintense in T2-weighted sequences. Our patient with a histologically confirmed sarcoidosis in the lungs showed liver lesions that were similar to sarcoidosis manifestations of the liver. Due to size, progression and overlapping features with secondary malignant liver lesions within an interval of 5 months, a biopsy was conducted and confirmed a primary hepatic lymphoma with diffuse large b-cells. Thus, we would recommend performing a biopsy in ambiguous lesions with indistinguishable characteristics and progression within a short follow-up interval.

