Myocardial dysfunction measured by tissue Doppler echocardiography in children with primary arterial hypertension
Justyna Zamojska1, Katarzyna Niewiadomska-Jarosik, Agnieszka Wosiak
1Department of Paediatric Cardiology and Rheumatology, 2nd Chair of Paediatrics, Medical University of Lodz, Lodz, Poland. j.zamojska@wp.pl.
Insights
Tissue Doppler echocardiography reveals impaired systolic and diastolic myocardial function in children with primary hypertension. These findings indicate potential cardiac deterioration in pediatric hypertension.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Imaging
- Hypertension Research
Background:
- Primary hypertension in children is a growing concern.
- Early detection of cardiac involvement is crucial for management.
- Tissue Doppler echocardiography offers advanced insights into myocardial function.
Purpose of the Study:
- To assess myocardial function in children with primary hypertension.
- To utilize tissue Doppler echocardiography (TDE) for evaluating systolic and diastolic parameters.
- To compare cardiac function between hypertensive children and healthy controls.
Main Methods:
- Echocardiographic evaluation of 64 children (34 hypertensive, 30 controls).
- Standard and tissue Doppler echocardiography parameters were employed.
- Assessment included systolic and diastolic function indices.
Main Results:
- Hypertensive children showed higher left ventricular myocardial performance index.
- Diastolic dysfunction was evidenced by altered E/A ratio and prolonged relaxation times.
- Tissue Doppler echocardiography revealed worse systolic (S', E') and diastolic (E'/A') parameters in hypertensive children.
Conclusions:
- Children with primary hypertension exhibit significantly impaired systolic and diastolic myocardial function.
- Tissue Doppler echocardiography is a valuable tool for detecting early myocardial changes in pediatric hypertension.
- These findings suggest potential myocardial deterioration in pediatric hypertension.
Background And Aim:
To evaluate myocardial function with the use of tissue Doppler echocardiography in children with primary hypertension.
Methods:
A total of 64 subjects (34 with hypertension, 30 control) underwent echocardiographic evaluation of systolic and diastolic function with the use of standard and tissue Doppler echocardiography parameters.
Results:
The left ventricular myocardial performance index was higher in children with hypertension (0.46 ± 0.08 vs. 0.35 ± 0.03; p < 0.01). The value of the A wave was higher in the hypertensive children group (0.59 ± 0.12 m/s vs. 0.49 ± 0.09 m/s; p < 0.01), while the E/A ratio was significantly lower in this group (1.58 ± 0.31 vs. 1.77 ± 0.28; p < 0.01). The values of isovolumetric relaxation time and deceleration time were significantly higher in patients with blood pressure elevation. The velocity of mitral flow propagation was lower (0.61 ± 0.08 m/s vs. 0.72 ± 0.10 m/s; p < 0.01) and E/Vp ratio was higher (1.50 ± 0.27 vs. 1.21 ± 0.23; p < 0.01) in hypertensive children. Evaluation of the left ventricle function with the use of tissue Doppler echocardiography showed significantly worse values of S' and E' septal, and S' and E' lateral in hypertensive children. The value of septal E'/A' ratio was lower in children with hypertension (1.52 ± 0.24 vs. 1.69 ± 0.25; p < 0.01), while the value of this index for lateral wall was similar. The values of E/E' septal and E/E' lateral were higher in patients with hypertension.
Conclusions:
In children with primary arterial hypertension, with the use of tissue Doppler echocardiography there are significantly lower values of diastolic and systolic parameters observed, which may be a sign of myocardial function deterioration.
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