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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
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Trigeminal neuralgia.

Joanna M Zakrzewska1, Mark E Linskey

  • 1Division of Diagnostic, Surgical and Medical Sciences, Eastman Dental Hospital, London, UK.

BMJ Clinical Evidence
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Summary
This summary is machine-generated.

This systematic review examines treatments for trigeminal neuralgia, a condition causing severe facial pain. It evaluates medications like carbamazepine and surgical options for patient relief.

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Area of Science:

  • Neurology
  • Pain Management
  • Evidence-Based Medicine

Background:

  • Trigeminal neuralgia is characterized by sudden, severe, unilateral facial pain.
  • Attacks occur in paroxysms, varying in frequency and duration.
  • The condition significantly impacts daily living and can lead to depression.

Purpose of the Study:

  • To systematically review the effects of ongoing treatments for trigeminal neuralgia.
  • To assess the effectiveness and safety of various therapeutic interventions.

Main Methods:

  • Systematic review of seven studies meeting inclusion criteria.
  • Searched major databases (Medline, Embase, Cochrane Library) up to September 2013.
  • Included harms alerts from regulatory agencies (FDA, MHRA).

Main Results:

  • Seven studies were included in the review.
  • A GRADE evaluation assessed the quality of evidence for interventions.
  • Information on effectiveness and safety of multiple treatments was gathered.

Conclusions:

  • The review presents data on baclofen, carbamazepine, gabapentin, and lamotrigine.
  • Effectiveness and safety of oxcarbazepine are discussed.
  • Information on microvascular decompression and destructive neurosurgical techniques is provided.