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Sleep to lower elevated blood pressure: study protocol for a randomized controlled trial.

Emer R McGrath1, Colin A Espie, Andrew W Murphy

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An online sleep intervention improved blood pressure in adults with hypertension and poor sleep quality. This study highlights the link between sleep health and cardiovascular risk management.

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Area of Science:

  • Cardiology
  • Sleep Medicine
  • Public Health

Background:

  • Poor sleep quality is linked to increased hypertension and cardiovascular disease risk.
  • Hypertension is a major risk factor for cardiovascular events like stroke and heart attack.
  • Managing blood pressure is crucial for reducing cardiovascular mortality.

Purpose of the Study:

  • To evaluate the effectiveness of an online sleep intervention.
  • To improve blood pressure control in individuals with hypertension and poor sleep.
  • To explore the impact of sleep quality on cardiovascular health.

Main Methods:

  • A Phase II, randomized-controlled trial involving 134 participants.
  • Participants had hypertension (systolic BP 130-160 mmHg) and poor sleep quality.
  • The intervention included sleep information, hygiene education, and cognitive behavioral therapy.

Main Results:

  • The primary outcome was the change in 24-hour ambulatory systolic blood pressure.
  • Analysis used intention-to-treat principles with a linear mixed model.
  • Results will determine the intervention's efficacy in reducing blood pressure.

Conclusions:

  • The study aims to demonstrate the clinical utility of digital sleep interventions.
  • Findings could support the integration of sleep management into hypertension care.
  • This research addresses a significant gap in managing cardiovascular risk factors through sleep improvement.