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Updated: Apr 22, 2026
Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
The association between left ventricular twisting motion and mechanical dyssynchrony: a three-dimensional speckle
Shohei Fujiwara1, Kazuo Komamura1,2, Ayumi Nakabo1
1Cardiovascular Division, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
Left ventricular (LV) dyssynchrony, a cause of heart dysfunction, is linked to LV twisting motion. Three-dimensional speckle tracking (3DT) can assess this relationship, aiding in diagnosing LV dyssynchrony.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Imaging
Background:
- Left ventricular (LV) dyssynchrony contributes to LV dysfunction.
- LV dyssynchrony is hypothesized to be associated with LV twisting motion.
Purpose of the Study:
- To evaluate the relationship between LV twisting motion and dyssynchrony using 3DT.
- To assess the acute effects of ventricular pacing on LV wall motion.
Main Methods:
- Utilized 3DT to measure LV twisting motion and dyssynchrony in 25 patients with sick sinus syndrome undergoing pacemaker mode switch.
- Calculated LV dyssynchrony based on the time to minimum peak systolic area strain in 16 LV segments.
Main Results:
- Ventricular pacing significantly increased LV dyssynchrony.
- Ventricular pacing led to decreased LV twist and torsion.
- A significant inverse correlation (r = -0.65, p < 0.01) was found between changes in LV dyssynchrony and torsion.
Conclusions:
- LV twisting motion evaluation shows potential for diagnosing LV dyssynchrony.
- 3DT is a viable tool for assessing LV dyssynchrony and its relationship with twisting mechanics.
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