Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Labeling DNA Probes03:31

Labeling DNA Probes

9.2K
DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
9.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Delphi survey to explore core curriculum for training the next-generation of hepatologists<sup>☆</sup>.

JHEP reports : innovation in hepatology·2026
Same author

Low muscle mass predicts liver-related outcomes in cirrhosis, independent of portal hypertension: A retrospective cohort study.

Canadian liver journal·2026
Same author

The Changing Etiological Landscape of Liver Cancer in the Era of Metabolic Disease.

Liver international : official journal of the International Association for the Study of the Liver·2026
Same author

Diagnostic innovation and models of care to improve fibrosis detection and risk stratification in steatotic liver disease.

The Lancet regional health. Europe·2026
Same author

A people-first, systems-oriented approach to liver disease in HIV infection.

Nature reviews. Gastroenterology & hepatology·2026
Same author

Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated With Impaired Health-Related Quality of Life in People With HIV.

Gastro hep advances·2026

Related Experiment Video

Updated: Jan 7, 2026

Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter
07:44

Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter

Published on: August 12, 2021

3.5K

NTBI unveiled by chelatable fluorescent beads.

Giada Sebastiani, Kostas Pantopoulos

    The Biochemical Journal
    |October 11, 2014
    PubMed
    Summary

    A new method accurately quantifies non-transferrin-bound iron (NTBI) in blood. This advancement in NTBI measurement could aid in diagnosing and managing iron overload disorders.

    Area of Science:

    • Biochemistry
    • Analytical Chemistry
    • Clinical Diagnostics

    Background:

    • Non-transferrin-bound iron (NTBI) is a marker in systemic iron overload and other pathologies.
    • Accurate NTBI quantification is crucial for disease diagnosis and management.
    • Current NTBI detection methods are often inaccurate and time-consuming.

    Purpose of the Study:

    • To develop a novel and accurate assay for measuring NTBI.
    • To improve the clinical applicability of NTBI assessment.

    Main Methods:

    • Development of a new assay for NTBI measurement.
    • Utilized an iron-sensitive fluorescent probe linked to magnetic beads.

    Main Results:

    • The novel assay demonstrates potential for NTBI quantification.

    More Related Videos

    Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
    12:20

    Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons

    Published on: August 6, 2014

    12.1K
    Bioluminescent Bacterial Imaging In Vivo
    05:06

    Bioluminescent Bacterial Imaging In Vivo

    Published on: November 4, 2012

    15.8K

    Related Experiment Videos

    Last Updated: Jan 7, 2026

    Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter
    07:44

    Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter

    Published on: August 12, 2021

    3.5K
    Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
    12:20

    Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons

    Published on: August 6, 2014

    12.1K
    Bioluminescent Bacterial Imaging In Vivo
    05:06

    Bioluminescent Bacterial Imaging In Vivo

    Published on: November 4, 2012

    15.8K
  • The method offers advantages over existing NTBI detection technologies.

    • Conclusions:

    • The developed assay may facilitate NTBI assessment in clinical settings.
    • This advancement could improve the diagnosis and management of iron-related disorders.