Related Experiment Video

Updated: Apr 22, 2026

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice
05:07

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice

Published on: August 25, 2023

2.2K

[Predictors of no-reflow phenomenon after primary percutaneous coronary intervention]

Bernardo M Rivera-Linares1, Martín Bedolla-Barajas, Jaime Morales-Romero

  • 1Servicio de Cardiología, Hospital Civil de Guadalajara "Doctor Juan I. Menchaca", Guadalajara, Jalisco, México. drmbedbar@gmail.com.

Revista Medica Del Instituto Mexicano Del Seguro Social
|October 11, 2014
PubMed

Insights

The no-reflow phenomenon occurs in 28.1% of ST-elevation myocardial infarction (STEMI) patients after primary percutaneous coronary intervention. Key predictors include Killip class II, multiple Q waves on ECG, angioplasty alone, and intracoronary thrombus.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Acute Myocardial Infarction Research

Background:

  • The no-reflow phenomenon is a frequent complication following primary percutaneous coronary intervention for ST-elevation myocardial infarction (STEMI).
  • Understanding its incidence and predictors is crucial for improving patient outcomes.

Purpose of the Study:

  • To determine the cumulative incidence of the no-reflow phenomenon in STEMI patients undergoing primary PCI.
  • To identify clinical and procedural predictors associated with the occurrence of no-reflow.

Main Methods:

  • Retrospective analysis of 71 STEMI patients.
  • Categorization into no-reflow and adequate reperfusion groups.
  • Logistic regression analysis to identify predictors.

Main Results:

  • Cumulative incidence of no-reflow was 28.1% (20 out of 71 patients).
  • Univariate predictors included elevated CK-MB, Killip class II, TIMI flow 0, multiple Q waves, reperfusion therapy type, and intracoronary thrombus.
  • Multivariate predictors identified: Killip class II (OR=9.3), ≥2 Q waves (OR=1.8), angioplasty alone (OR=19.9), and intracoronary thrombus (OR=11.9).

Conclusions:

  • Early identification of predictors like Killip class II, ECG findings, reperfusion strategy, and thrombus presence is vital.
  • Implementing targeted measures based on these predictors can help reduce the incidence of no-reflow phenomenon.
Abstract

Keywords:
Myocardial infarctionNo-reflow phenomenonPredictorPrimary percutaneous coronary intervention

More Related Videos

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.0K
Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

2.8K

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
490
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
512
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
1.2K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
762