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Related Experiment Video

Updated: Apr 22, 2026

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
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Postoperative nausea and vomiting.

Young Eun Moon1

  • 1Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, Catholic University College of Medicine, Seoul, Korea.

Korean Journal of Anesthesiology
|October 11, 2014
PubMed
Summary
This summary is machine-generated.

Postoperative nausea and vomiting (PONV) remains a challenge due to complex mechanisms. This review covers PONV pathogenesis, new preventive drugs, and pharmacogenetics for future research.

Keywords:
Postdischarge nausea and vomitingPostoperative nausea and vomitingPrevention

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Area of Science:

  • Anesthesiology
  • Pharmacology

Background:

  • Postoperative nausea and vomiting (PONV) is a persistent clinical issue despite extensive research.
  • The complex pathophysiology of PONV necessitates ongoing investigation and improved management strategies.

Purpose of the Study:

  • To review the underlying mechanisms of PONV pathogenesis.
  • To summarize current preventive treatments, including novel pharmacotherapies and updated clinical applications of established drugs.
  • To explore emerging trends in postdischarge nausea and vomiting and the role of pharmacogenetics in PONV.

Main Methods:

  • Literature review focusing on PONV pathogenesis.
  • Analysis of recent meta-analyses on the clinical use of antiemetic drugs.
  • Synthesis of current research on postdischarge nausea and vomiting and pharmacogenetics.

Main Results:

  • PONV mechanisms are complex and not fully elucidated.
  • New drugs and refined use of existing medications offer improved PONV prevention.
  • Pharmacogenetics presents a promising avenue for personalized PONV management.

Conclusions:

  • Effective PONV management requires understanding its complex mechanisms.
  • Future research should address current study limitations and explore pharmacogenetic approaches for personalized treatment.
  • Optimizing PONV prevention involves integrating novel therapies and evidence-based practices.