Related Experiment Video
Updated: Apr 22, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Methicillin resistant Staphylococcus epidermidis induced endogenous endophthalmitis.
Undrakonda Vivekanand1, Pradeep Pakalapati2, Gudimetla Sandeep Reddy3
1Associate Professor, Department of Ophthalmology, Alluri Sitarama Raju Academy of Medical Sceinces , Malkapuram, Eluru, West Godavari, Andhra Pradesh, India .
Fulminant endogenous endophthalmitis is a rare infection. This case highlights methicillin-resistant Staphylococcus epidermidis as a cause following platelet transfusion and antibiotic treatment for suspected dengue fever.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endogenous endophthalmitis is a rare intraocular infection.
- Typically associated with hematogenous spread of bacteria or fungi.
- Often observed in immunocompromised individuals.
Observation:
- A case of fulminant endogenous endophthalmitis is presented.
- The causative agent identified was methicillin-resistant Staphylococcus epidermidis (MRSA).
- The infection occurred after platelet transfusion and intravenous antibiotic therapy for suspected dengue fever.
Findings:
- Methicillin-resistant Staphylococcus epidermidis can cause severe endogenous endophthalmitis.
- Platelet transfusion and antibiotic therapy may be associated with this rare complication.
- This case expands the known spectrum of MRSA-related endogenous endophthalmitis.
Implications:
- Highlights the importance of considering rare infections in patients receiving transfusions or antibiotics.
- Suggests vigilance for intraocular infections in patients with risk factors.
- Underscores the need for prompt diagnosis and management of endogenous endophthalmitis.
More Related Videos
Related Concept Videos
Endocarditis I: Introduction
Clinical Significance of Antibiotic Resistance
Staphylococcal Skin Infections
Microbiome of the Eye
Mechanism of Antibiotic Resistance in MRSA
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.

