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Updated: Apr 22, 2026

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
Quality assessment of randomized clinical trial in intensive care
Giulliano Peixoto Gonçalves1, Fabiano Timbó Barbosa1, Luciano Timbó Barbosa2
1Liga de Anestesiologia, Dor e Terapia Intensiva de Alagoas, Universidade Estadual de Ciências da Saúde de Alagoas, Maceió, AL, Brasil.
Objective:
A randomized clinical trial is a prospective study that compares the effect and value of interventions in human beings, of one or more groups vs. a control group. The objective of this study was to evaluate the quality of published randomized clinical trials in Intensive care in Brazil.
Methods:
All randomized clinical trials in intensive care found by manual search in Revista Brasileira de Terapia Intensiva from January 2001 to March 2008 were assessed to evaluate their description by the quality scale. Descriptive statistics and a 95 % confidence interval were used for the primary outcome. Our primary outcome was the randomized clinical trial quality.
Results:
Our search found 185 original articles, of which 14 were randomized clinical trials. Only one original article (7.1%) showed good quality. There was no statistical significance between the collected data and the data shown in the hypothesis of this search.
Conclusion:
It can be concluded that in the sample of assessed articles 7% of the randomized clinical trials in intensive care published in a single intensive care journal in Brazil, present good methodological quality.
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