Stenotrophomonas maltophilia Pseudo-outbreak at a University Hospital Bronchoscopy Unit in Turkey

G Ece1, B Erac2, M H Limoncu2

  • 1Department of Medical Microbiology, Izmir University School of Medicine,Yeni Girne Boulevard, 1825th Street, 12 Karsiyaka, Izmir, Turkey. gulfem.ece@gmail.com.

Abstract

Insights

This study found identical Stenotrophomonas maltophilia strains during bronchoscopy, suggesting potential equipment contamination. Implementing strict cleaning protocols halted further S. maltophilia isolation, highlighting the importance of disinfection in preventing pathogen spread.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Stenotrophomonas maltophilia is an opportunistic pathogen frequently found in healthcare settings.
  • Its spread is often linked to invasive procedures, diagnostic tools, and antibiotic misuse.
  • Bronchoscopy is a common procedure where pathogen transmission can occur.

Purpose of the Study:

  • To investigate consecutive isolations of S. maltophilia from bronchoalveolar lavage samples during bronchoscopy.
  • To determine the clonal relationship between S. maltophilia isolates obtained within a short timeframe.

Main Methods:

  • Collected bronchoalveolar lavage samples from four patients with S. maltophilia during bronchoscopy.
  • Identified isolates and assessed antibiotic susceptibility using the Vitek 2.0 system.
  • Analyzed clonal relatedness via enterobacterial repetitive intergenic consensus (ERIC) PCR.

Main Results:

  • Four consecutive S. maltophilia isolates exhibited identical band patterns on ERIC PCR, indicating clonal relatedness.
  • The findings suggest a potential common source of infection, possibly related to the bronchoscopy procedure.

Conclusions:

  • Consecutive S. maltophilia strains with identical genetic profiles were identified within a week during bronchoscopy.
  • Adherence to appropriate disinfection and cleaning protocols effectively prevented further isolation of the pathogen.
  • This highlights the critical role of instrument decontamination in preventing healthcare-associated infections.

Related Concept Videos

Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
73
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
1.0K
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
52
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
787
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture01:26

Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture

Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
1.2K
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
1.1K