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Updated: Apr 22, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Laparoscopic versus open resection for transverse colon cancer
Massimiliano Mistrangelo1, Marco Ettore Allaix, Paola Cassoni
1Digestive and Colorectal Surgical Department, Città della Salute e della Scienza di Torino Hospital, Centre of Minimal Invasive Surgery, University of Turin, Corso A. M. Dogliotti, 14, 10126, Turin, Italy, mistrangelo@katamail.com.
Laparoscopic resection (LR) for transverse colon cancer is feasible and safe, showing similar short-term outcomes and survival rates compared to open resection (OR). Further studies are needed to confirm long-term oncological equivalence.
Area of Science:
- Colorectal Surgery
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Limited data exists on laparoscopic resection (LR) versus open resection (OR) specifically for transverse colon cancer.
- Previous trials have not isolated outcomes for this specific tumor location.
Purpose of the Study:
- To evaluate the feasibility and safety of laparoscopic resection for transverse colon cancer.
- To compare outcomes of LR versus OR for transverse colon cancer with existing literature.
Main Methods:
- Retrospective analysis of 123 patients with transverse colon adenocarcinoma.
- Comparison of laparoscopic resection (LR) and open resection (OR) groups.
Main Results:
- Laparoscopic resection (LR) showed significantly earlier return of bowel function and shorter hospital stays.
- No significant differences in operating time, blood loss, 30-day complications, mortality, or 5-year survival rates were observed between LR and OR.
- Conversion rate from LR to OR was 16.7%.
Conclusions:
- Laparoscopic resection (LR) is a feasible and safe approach for transverse colon cancer with comparable short-term outcomes to open resection (OR).
- Long-term oncological outcomes and equivalence require further investigation through larger prospective studies.

