Related Experiment Video
Updated: Apr 22, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Recurrence of idiopathic sudden sensorineural hearing loss: a retrospective cohort study
Che-Ming Wu1, Kuan-Ji Lee, Shih-Lun Chang
1*Department of Otorhinolaryngology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou, Taoyuan, Taiwan; †Department of Otolaryngology, Chi Mei Medical Center, Tainan City, Taiwan; ‡Department of Medical Research, Chi Mei Medical Center, Tainan City, Taiwan; §Department of Hospital and Health Care Administration, Chia-Nan University of Pharmacy and Science, Tainan City, Taiwan; and ∥Center for General Education, Southern Taiwan University of Science and Technology, Tainan, Taiwan.
Objective:
To explore the recurrence rate of idiopathic sudden sensorineural hearing loss (ISSNHL).
Design:
Using the Taiwan Longitudinal Health Insurance Database, we compared in a retrospective cohort study 45,715 patients with ISSNHL between January 2001 and December 2006 with 45,715 age-, gender-, and comorbidity-matched controls without ISSNHL. We followed each patient from 180 days after the initial diagnosis until the end of 2009 and evaluated the incidence of ISSNHL for 3 years minimum.
Results:
The cumulative incidence of ISSNHL recurrence was 4.99%. Cox proportional hazard regressions showed that the 50- to 64-year-old age group had a higher adjusted hazard ratio (1.59; 95% confidence interval: 1.40-1.81) than did the 0- to 34-year-old age group. Different comorbidities did not significantly affect the incidence of ISSNHL relapse.
Conclusions:
The risk of an ISSNHL relapse in patients with a history of ISSNHL was higher than was the risk of a first occurrence of ISSNHL in the Controls. We suggest that physicians counsel patients with a history of ISSNHL to seek medical attention if they have hearing impairments because they may also have a high risk of an ISSNHL relapse.
Evidence Level:
2B.
More Related Videos
Related Concept Videos
Unrenewable Cells
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of...
Auditory Pathway
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
The Cochlea
Hair Cells
Hearing

