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Phenotypes influencing low physical activity in maintenance dialysis
Marine Panaye1, Anne Kolko-Labadens2, Catherine Lasseur3
1Néphrologie, Hôpital E. Herriot, Lyon, France.
Summary
Dialysis patients exhibit very low physical activity (PA) levels, with most being sedentary. Addressing modifiable patient factors could enhance PA, potentially improving health outcomes and quality of life.
Area of Science:
- Nephrology
- Exercise Physiology
- Epidemiology
Background:
- Physical inactivity is a significant risk factor for mortality in patients undergoing maintenance dialysis.
- The extent and determinants of physical activity in this population are not well-documented.
Purpose of the Study:
- To evaluate the weekly physical activity (PA) levels in a large cohort of dialysis patients.
- To identify determinants associated with physical activity in this population.
Main Methods:
- A prospective national epidemiological study involving 1,163 maintenance dialysis patients (hemodialysis and peritoneal dialysis).
- Daily step counts were recorded over seven consecutive days using pedometers.
Main Results:
- Sixty-three percent of patients were sedentary (<5000 steps/day), with a median of 3,688 steps/day.
- Physical activity decreased with age, with 83% of patients over 80 years being sedentary.
- Lower PA was associated with inflammation, cardiovascular disease, protein energy wasting, obesity, and diabetes; higher PA was linked to prior kidney transplantation and greater muscle mass.
Conclusions:
- Dialysis patients demonstrate critically low physical activity and high sedentary behavior.
- Targeting modifiable patient phenotypes offers a potential strategy to increase PA, thereby improving morbidity, mortality, and quality of life.
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