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Movement of microtubules by single kinesin molecules
J Howard1, A J Hudspeth, R D Vale
1Department of Physiology, University of California School of Medicine, San Francisco.
Nature
|November 9, 1989
Abstract:
Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles along microtubules. Using a new technique for measuring the movement produced in vitro by individual kinesin molecules, it is shown that a single kinesin molecule can move a microtubule for several micrometers. New information about the mechanism of force generation by kinesin is presented.